● Actively RecruitingPhase I/II/III

Paid Sickle Cell Disease Clinical Trials

Sickle cell disease clinical trials recruiting. Access gene therapies and new treatments. Compensation up to $5,000. Studies for adults and adolescents.

Compensation

$2,500 - $5,000

Duration

52-104 weeks

Phase

Phase I/II/III

FDA Regulated

IRB Approved

GCP Certified

Who May Qualify

  • Age 12-65 years (varies by study)
  • Confirmed sickle cell disease (SS, SC, or S-beta thalassemia)
  • History of vaso-occlusive crises
  • Adequate organ function
  • Willingness to use contraception throughout study
  • Compliance with current treatment regimen

Who May Not Qualify

  • Red blood cell transfusion in past 60 days (for some studies)
  • History of stroke
  • Iron overload requiring chelation
  • Ongoing pregnancy
  • Prior stem cell transplant (unless study-specific)

Frequently Asked Questions

What sickle cell treatments are being studied?

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Studies include gene therapy and gene editing (one-time potentially curative treatments), new medications to prevent sickling, anti-inflammatory treatments, and drugs to reduce vaso-occlusive crises.

What are gene therapy studies like?

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Gene therapy typically involves collecting your stem cells, genetically modifying them, and reinfusing them after chemotherapy. This is a more intensive process than medication studies and may require extended hospitalization.

How are pain crises tracked during the study?

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You will maintain a diary of pain episodes, healthcare visits, and treatments. Studies aim to reduce the frequency and severity of vaso-occlusive crises.

Can I continue taking hydroxyurea?

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Requirements vary by study. Some trials allow stable hydroxyurea, while others require discontinuation. Gene therapy studies typically require stopping disease-modifying medications.

Check Your Eligibility

Step 1 of 3Age Verification

Participants must be at least 18 years old