● Actively RecruitingPhase II/III

Paid Ulcerative Colitis Clinical Trials

Ulcerative colitis clinical trials recruiting now. New JAK inhibitors and biologics being studied. Compensation up to $3,500 for qualifying participants.

Compensation

$1,800 - $3,500

Duration

16-52 weeks

Phase

Phase II/III

FDA Regulated

IRB Approved

GCP Certified

Who May Qualify

  • Age 18-75 years
  • Diagnosis of ulcerative colitis for at least 3 months
  • Moderate-to-severe active disease (Mayo score 6-12)
  • Endoscopic subscore of 2 or higher
  • Inadequate response to at least one conventional therapy
  • Disease extending at least 15 cm from anal verge

Who May Not Qualify

  • Crohn's disease or indeterminate colitis
  • Fulminant colitis or toxic megacolon
  • Prior colectomy or planned surgery
  • CMV colitis
  • Current use of IV corticosteroids

Frequently Asked Questions

What medications are being studied for ulcerative colitis?

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Trials are evaluating new biologics (anti-IL-23, anti-integrin), oral JAK inhibitors, S1P modulators, and novel small molecules. Options exist for patients who are new to biologics or have failed prior treatments.

How often will I need a colonoscopy?

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Most studies require flexible sigmoidoscopy or colonoscopy at screening and at key timepoints (usually week 8-12 and end of study) to assess mucosal healing.

Can I continue my current UC medications?

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Oral aminosalicylates are usually permitted at stable doses. Corticosteroids may be allowed initially but are typically tapered. Biologics require a washout period.

What is the main goal of these studies?

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Studies typically aim to achieve clinical remission (resolution of symptoms) and endoscopic improvement or healing. Many also evaluate quality of life and long-term disease control.

Check Your Eligibility

Step 1 of 3Age Verification

Participants must be at least 18 years old